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????????????????Kopsia officinalis Tsiang et P.T.Li

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????????????????????????????????估????????????壬????????????????????????1-1.5cm???????????????????????Σ???12-17cm????3.5-5.5cm?????????????Ш?Σ?????????????????????????20??????ɡ?????????????棬???42????????????????14cm???????С????????????5??????????????????У????????????????н????????1????????壻??????????????????????????????????????????????5??????????????5???????????????????????2?????????ε???????????????????????????????????????????????2.5cm????????????2??????????Σ???????????????2???????4-9???????9-12???

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????????????????500-800m????????л????·???

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???????????????????????з?????16?????????????13????????????????????eburnamenine????????????kopsanone????5??18-???????????飨5??18??dioxokopsane???????????????kopsinilamine?????????????kopsinine???????????pleio-carpine?????????????kopsamine????N-??????-12-????????????????N??carbomethoxy??12??methoxykopsinaline????N-??????-11??12-??????????????????N??carbomethoxy??11??12??dimethoxykop-sinaline????????????????????????vincadifformine????N-??????-11-???-12-????????????????N??carbomethoxy-11-hydroxy-12-methoxy-kopsinaline????N-??????-11-??????-12-?????????????N??carbomethoxy??11??methoxy??12??hydroxykopsinaline????N-?????????????kopsamine N-oxide??[1]??

????????á????????? ????????????24h???200mg/kg???Σ????8h????????????CCl4??????С????????????????ALT????????????????AST??????????????????????????CCl4????????????????????????????????????Ч???????ALT????????????????????????????????????????????????????????????????????????????????Ч?????????????????????????????????С???????????????????Ч???????ж?????????????????????????????????????á??????????????????????7d??????С?????AIT??AST????????????ALT??????????????0??5??mol??L?????????????????????????CCl4?ж?С???AIT??????????????????20mg??kg???3d??????????г?С????????????????????????????????????DNA RNA????????????[1]????????1mmol??L??????????????????????CCl4???????????????????MDA?????????????????????????????????????MDA??????????????俹CCl4??????????????????????????????P-450??????????24h????????????CCl4?????????????????????????????????14CCl4???????????????????????????????????????俹CCl4????????????????????????????CCl4???????????????[2]??