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?????????J??n Zh??n J?? Hu??

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????????????????Calendula Officinalis L.

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????????????? ???????????????????30-60cm??????ж?????????????????????з????????????????????Σ?????????????????????????????Σ???5-9cm????1-2cm????????????????????Σ?????????????????????????????????????????2.5-5cm???й??????????1-2????????Σ???????????????????????????????????1-2??????????????????3?????????????????????????5?????????????????????????????????????????????秣?????????????????????4-7???

?????????????? ?????????λ???????Σ????1.5-4cm?????1-2????????????????Σ?????????????1-2?У??????????????????????????е???????????????е?????????????ζ??????

??????????????????(stismasterol),??-?????(??-silosterol),???????(campesterol),?????(cholesterol),24-?????????(24-methylenecholesterol),???????????(isofucosterol),4??-???7,24(28)-???????-3??-??[4??-methylstigmasta-7,24(28)-diene-3??-ol], 4??-????????-7,24(28)-???-3??-??[4??-methyler-gasta-7,24(28)-diene-3??-ol],??????(methyl sterol),???????(avenasterol),??-???????(??-amyrin),??-???????,???????(taraxasterol),??-???????(??-taraxasterol),???????(lupeol),????????(brein),????????(calenduladiol),??????(srnidiol),??????(faradiol),?????????(ursa-diol)????????(erythrodiol),??????????(manilladiol),?????????(lupenetriol),?????????(heliantriol)F??C,?????????(ursatriol),??????(longispinogenine),??-?????????(phydroxybenzoic acid),??-????(p-coumaric acid),??????(gen-tisic acid),?????(vanillic acid),??????(syringic acid),??????(caffeic acid),??-?????????(o-hydroxyphenyl acetic acid),?????(salicylic acid),???????(protocatechuic acid),ɡ?λ?????(umbelliferone),????????(esculetin),???????(scopoletin),????????(calendin),???????????????(calendoflaside),????????(calendoflavoside),????????????(calendoflavobioside),????(narcissoside,narcissin),?????(quercetin),??????(isoquercetin),??????(rutinoside),????????(isorhamnetin),????????-3-O-???????(isorhamnetin-3-O-glucoside),????????-3-O-?????(isorhamnetin-3-O-neohes-peridoside),????????-2G-??????????????(isorhamnetin-2G-rhamnosylrutinoside),????????????(quercetin glucoside),?????-2G-?????????????(quercetin-2G-rhamnosylrutlnoside),?????-3-O-?????(quercetin-3-O-neohesperidoside),????????-3-O-??-L-??????????(1??2)-O[??-L-??????????(1??6)]-??-D-??????????

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1.???????????????????п?????????????,????????????????????Ч????á??俹????????????????????????????????Ч????á????? 45%??????????п???????, 80%?????????п???????,?????????????????????????????????????10??90?????????п?????????????????????????,10mg/ml??25mg/ml????????????????Ч?????з?????????????????????????????????,????????????????????п??????á??????????????[FS:PAGE]?á?????????????????γ?????,?????????е?????????й?,????????1??50 000?,?????????????????????ж??????ATR-8??A2 Frunze flu virus???????????,????С??A2 Frunze flu virus??????????????δ???????????

2.???????????????е?????????????????????15-50g/kg,??12????,???????嵨?????????????????????-???????????????????,???????????????????????????н??????á???????????????????????????????????????????????????????????????????????????S2??С???????,??????е???????????????????????

3.?????????????????????????????????,?????????????С???????????????????á???????е??????????????????????????????,?????????????????????á??????????????,????PS.?? 10-5-10-6mg/ml????????????54%-100%??

4.?????????????????????????????????,???????????????????????????????,??????????,???????????,?????????????????????????????????,????????????,????????????????? ?????????????????,??????????????????????? calephlone???????????????????,0.05g/kg/????????????????????б??????á? ??????п??????,???????????????????????????????С?С??????????????,????????????1200??g????,????????????20%?????????????????75??g????????????????????????ó??????????,???1200??g?????70.7%???????