?????????--???л??????
?????????D?? M?? Y?? P??i L??n
???????
????????????????????????????
????????????????Eupatorium cannabinum L.
??????????????δ??????????????????????????ɡ?
????????????????? ?????????????50-150cm????????????н???????????????????????????????????????????????????ɡ??????????????????????????????????????????????????????????????????????ж?????????0.5cm????????????????????????????λ??????Σ???6-11cm????2-3cm????????????????Ш?λ??Ш?Σ????????С???????????Σ?????????С???????????????????????????????????????????????????????????????漰????????????????????о????????????????????????????????ɡ??ɡ?????????????????6mm????3-7??С???????????????6mm????3-7??С????????9-10????2-3???????????????Σ????2mm?????汻?????????????????????????Σ???5-9mm????????????????????????????????????????????????5mm??????????????????????????????3mm??5??????????????????????5mm??
???????????
?????????????????????丽?????????
?????????????????????
???????
???????????????,?????,???????????????,?ж??,??????,?????????,?????????????????????,????????????????λ???????,??6-11cm,??2-3cm,??????????,????Ш?λ??Ш??,????????С???????,ζ?????
??????? ????????±????????????????,????????,????Χ?????????з????????????,???????????????????,????????,??4-6????????,??90-130-160??m,???12-16??m,???????????????,??2-7????????,??76-300??m,???18-48??m,???????????4????????,???40-50??m???????????????????
??????棺???????????±???????????????????,??????????????????2??,???????,??2????????????ɡ????,????????????????????????6???????????,????????з???????????????±???????2-3?????????
???????棺?????????Ρ?????????С,???λ????,????????????????????????3-10???????,????????8-10??20?????С??????????????,???紦????????????????,????????????????????,???????,С???????????????????????????γ?????2-3?г????????????????????,??????С????????,???з????????
?????????
1???????????????????,??????????????????(supinne),???????(echinatine),??????(trachelanthamine),??-?????????????(??-bu-tyrylsupinine),??-???????????????(??-valeryl-supinine),??-???????????(??-acetylechinatine),??-?????????????(??-isovalerylechinatine),??-??????/??????????????(??-angeloyl/tigloyl supinine),??-??????/????????????(??-angeloyl/tigloylechinatine)??-??????/???????????(??-angeloyl/tigloyltrachelanthamine)?????????????????????????????(eupatolide),????????(eupatoriopicrin),3-????????-20-???????????(3-acetoxy-20-deoxyeupatoriopicrin),3-????????-?????????????(3-acetoxy-dideoxyeupatoriopicrin),3??-???????????(3??-hydroxyeupatoriopicrin),?????????????(eucannabino-lide),????????-19-O-????????(eupatoriopic[FS:PAGE]rin-19-O-1inolenate),8??-???????-2??-???????????(8??-acetoxy-2??-hydroxycos-tunolide),2-??????-8??-(4,5-??????????????)???????????[ 2-acetyl-8??-(4,5-dihydroxytigloyloxy)preeupatundin],6-???????????(6-hydroxytremetone),?????????????(sachalinin),3??-??????????6-???????????(3??-angeloyloxy-6-hydrox-ytremetone),3??-?????????-6-???????????(3??-methacry-loxy-6-hydroxytremetone),3??-????????-6-???????????(3??-isobutyryloxy-6-hydroxytremetone),???????????????????(cannaclerodanolide),?????????(alantolactone),???????????(isolantolanctone),???????( hiyodorilactone)E,????????????????(desacetoxy hiyodorilactone)B,???????????(eupaformonin)???
2????????????????????(hispidulin),Ш???????(eupafolin),??????(astragalin),??????(hyperoside),????-3-??????( kaempferol 3-rutinoside),??????(isoquercitrin),????(rutin),????????(pectolinari-genin),4??,5,7-?????-3??,6-???????????(jaceosidin),5,7-?????-3, 4??, 6-??????????(santin),????????(centaureidin)???
3????????????????(stigmasterol),??-?????(??-sitosterol),??????? (campesterol),???????(taraxasterol)????????????????(euparin),10-???????????????????(10-acetoxynerylacetate),?????(lutein), 4-??????????(4-hydroxyionone),(E)-1-?????[(E)-hex-1-enoic acid],??????(germacrene)D,??????????(neryl acetate),????????????(nerylisovaler-ate),??????????(neryl isobutyrate),??????????????(dammaradienyl acetate)???
4???????????????? 0.3%,???У??????(n-octanal),?????????(hexylacetate),?????(n-nonanal),?????????(heptylacetate),???(decanal),??????????(octyl acetate),????????(methyl salicylate),??????????(linalyl acetate),??????????(bornyl acetate),???????????(lavandulyl acetate), ?????-3-???????(3-hexenyl tiglate),??????????,?????????(ben-zyl acetate),???????????(geranylacetate),??????é????(citronellyl acetate),??????????(bornyl propionate),???????????????(thymohydroquinone dimethylether),?????-???????(??-terpenylpropionate),??????????(nerylpropioriate),????????????(thymylbutyrate),????????????(bornylisovalerate),?????-???????(??-terpenyl butyrate),??-3-?????????????( cis-3-hexenyl benzoate),??????????????(thymylisovalerate),????????????,?????????????(geranylisovalerate),?????????????(thymyltglate),??????????( benzylbenzoate)???????,????????к?2-?????-5-?????????(2-isopropyl-5-methylanisole)??38?????
????????á?
1.?????????????????????????С?????????ж??????,???????б?????????????,???ж????????Ч?????е?????????????????к??е??????п???????????á?
2.????????????С?????????????????,??????????е??????????????н????????????,ID50??1??g/m1-2??g/ml????????????????Щ?????????á?
3.????????????????????е?????????????????????????????????????,????????????????
????ζ??ζ???????
?????????Ρ?????????????????????????????????а????????????????????
???÷??????????????????4-9g??
?????????л??????