????λ?????? > ?????? > ?????? > ??????C > ?????

?????

?????????C?? F??i Zh?? Y??

???????

???????????????????鼵?????

????????????????Cephalotaxus sinensis (Rehd.et Wils.)Li[C.drupacea Sieb.et Zucc.var.sinensis Rehd.et Wils.]

?????????????????＾???????ɡ?

?????????????С????????15m?????????????????????????????Σ????2?У???2-5cm?????3mm?????????????????????????????Σ????????????????????????????????2??????????????????????2-4????????6-7?????????????6mm????????3mm??????????Σ???????1??????????4-11??????????????2-5?????鷢?????????????2-5???????????????????Ρ?????????λ?????Σ???1.8-2.5cm??????????м????????3-4???????10-11?????

???????????

?????????????????????????????????????????????????????????????????????????

????????????????????????????????????????????????????????????????????????

????????????????????(cephalotaxine)????-??????????(??-hydroxycephaltaxine)?????????????(drupacine)??????????????(demethylcephalotaxinone)??C-3-????????????(C-3-epiwilsonine)????????????(wilsonine)?????????????????(hainanolide)?????鼼?(isoharringtonine)?????鼼?(homoharringtonine)????????????鼼?(harringtonine)???????鼼?(deoxyharringtonine)??

????????á????????з??????????䴙???鼼䴙???鼼????????ú????鼵???????????????????????????????????????????????Ч??

????ζ??????????

?????????Ρ?????????????????????????

???÷???????

?????????????????????????????÷?????1.???????? ???л??????????????50-100mg?????????????200mg.??????????????????11????????????????3????????????????2????δ????4?????????????????????????н????Ч?????μ??????????????10??????????????????6-????????????????????????1?????????????????????????6?????????????????4???????????2?????????5????

2.????????????????? ????????????7??9?Σ????????3???Σ???Ч4?дΣ?????1???Ρ???????????8???Ρ???????????????????65.5-133mg??????97.8mg?????32-42d?????36d????Ч????????????62.5-126mg?????92.5mg?????28-50d?????40d????Ч???????????????????Ч???????????????????????????????????????